基于深度学习的多STBC盲识别算法

针对空时分组码(space-time block code, STBC)识别中多种编码类型难区分的问题, 提出了一种基于卷积神经网络的STBC盲识别算法。该算法首先将接收信号采用自相关函数的频域预处理, 输入到卷积神经网络中对信号特征进行提取, 全连接层对特征进行映射, 实现对6种STBC类型的识别。仿真实验结果表明, 在无信道和噪声等先验信息的条件下, 所提算法能够有效区分3种相似度高的STBC3码, 且将STBC可识别的编码类型由目前的4种扩充到6种, 识别准确率能达到96%。该方法的复杂度较低, 不需要利用大量样本数据, 实时性高, 具有较好的工程应用价值。     

基于正交实验的透气砖座砖中尖晶石含量的优化

实验根据不同粒度和多少的尖晶石对透气砖座砖常温和高温下强度以及重烧线变化、热震稳定性能的影响,采用正交设计法来确定最佳粒度的尖晶石的加入量。研究结果表明,尖晶石a粒度、b粒度、c粒度掺量分别为6%、10%、4%时,试样具有最好的使用性能。     

The molecular role of the Rothmund-Thomson-, RAPADILINO- and Baller-Gerold-gene product, RECQL4: recent progress

The RecQ family of DNA helicases is highly conserved throughout evolution and plays an important role in the maintenance of genomic stability in all organisms. Mutations in three of the five known family members in humans, BLM, WRN and RECQL4, give rise to disorders that are characterized by predisposition to cancer and premature aging, emphasizing the importance of studying the RecQ proteins and their cellular activities. Interestingly, three autosomal recessive disorders have been associated with mutations in the RECQL4 gene: Rothmund-Thomson, RAPADILINO, and Baller-Gerold syndromes, thus making RECQL4 unique within the RecQ family of DNA helicases. To date, however, the molecular function of RECQL4 and the possible cellular pathways in which it is involved remain poorly understood. Here, we present an overview of recent findings in connection with RECQL4 and try to highlight different directions the field could head, helping to clarify the role of RECQL4 in preventing tumorigenesis and maintenance of genome integrity in humans. Received 31 October 2006; received after revision 4 January 2007; accepted 5 February 2007     

How do Shp2 mutations that oppositely influence its biochemical activity result in syndromes with overlapping symptoms?

Activating and inactivating mutations of SHP-2 are responsible, respectively, for the Noonan (NS) and the LEOPARD (LS) syndromes. Clinically, these developmental disorders overlap greatly, resulting in the apparent paradox of similar diseases caused by mutations that oppositely influence SHP-2 phosphatase activity. While the mechanisms remain unclear, recent functional analysis of SHP-2, along with the identification of other genes involved in NS and in other related syndromes (neurofibromatosis-1, Costello and cardio-facio-cutaneous syndromes), strongly suggest that Ras/MAPK represents the major signaling pathway deregulated by SHP-2 mutants. We discuss the idea that, with the exception of LS mutations that have been shown to exert a dominant negative effect, all disease-causing mutations involved in Ras/MAPK-mediated signaling, including SHP-2, might lead to enhanced MAPK activation. This suggests that a narrow range of MAPK signaling is required for appropriate development. We also discuss the possibility that LS mutations may not simply exhibit dominant negative activity. Received 30 November 2006; received after revision 8 February 2007; accepted 13 March 2007     

SARS研究进展

本文对SARS病原学、流行病学、预防和治疗的研究进展进行了综述。     

代谢综合征的流行病学调查与分析

目的：了解20岁以上成年人代谢综合征的发生率；对比分析其相关的危险因素及保护因素。方法：(1)通过1026名20岁以上成人体检，应用修订的代谢综合征的美国诊断标准，凡具备以下5项标准中3项及3项以上，即①体质指数(BMI)≥24，②甘油三酯ρ(TG)≥150mg／dL，③高密度脂蛋白胆固醇ρ(HDL—C)男＜40mg／dL、ρ(HDL—C)女＜50mg／dL，④空腹血糖ρ(FBC)≥110mg／dL，⑤收缩期血压(SBP)≥130mmHg或舒张期血压(DBP)≥85mmHg或SBP／DBP≥130mmHg／85mmHg(1mmHg＝0．133kPa)，诊断为代谢综合征，共检出136名为病例组。(2)从既往无高血压、糖尿病、冠心病及血脂异常史，且本次筛检未纳入代谢综合征的人群中，抽取与病例组性别、年龄相当的136名进行配对调查分析，计算其相关因素的χ^2值、P值、机会比(OR)值，以及机会比值的95％可信限(OR 95％CI)。结果：(1)从1026名中共检出代谢综合征136名，其发生率为13．26％；(2)调查分析发现摄入过量和长时间处于坐位而又缺乏运动两项可能为代谢综合征的危险因素；而运动可能是代谢综合征的保护因素。结论：(1)本次广东地区部分人群筛查20岁以上成人代谢综合征的发生率为13．26％，虽较美国人为低，但中年组为17．48％，老年组高达29．27％，必须引起重视；(2)坚持终身运动和合理膳食可能是预防代谢综合征的切实可行、经济、有效的措施。     

径向电磁离合器

一种新型结构的电磁离合器 ,可替代电磁联轴器。文中对这种离合器的工作原理、结构设计、参数选取和传动扭矩作了分析并给出了一种结构型式。试验样机证实了其工作原理的正确     

新型薄壁柴油机缸体铸件的研制与应用

采用低合金化、合锑多元复合孕育剂、扫描电镜、200h台架试验、以及l000h耐久试验等方法对新型薄壁柴油机缸体铸件进行了研制与应用试验．试验结果表明：碳当量控制在3．9％--4．1％时(与菲亚特缸体的碳当量大体相当)，采用低合金化及合锑复合孕育剂，可稳定获得高强度铸件，抗拉强度σb＞270MPa，硬度HB＞210，白口倾向小，硬度差小于35HB，其性能均达到菲亚特缸体的性能要求．对无缸套缸体的缸壁表面进行激光处理，比传统缸套的耐磨性提高一倍以上．由于采用了无缸套缸体生产技术，简化了柴油机的结构，降低了柴油机的生产成本，提高了柴油机使用性能和技术含量．     

砌块建筑墙体构造与节能发展动态

从原料性能、生产工艺、产品质量等方面探讨了生产混凝土小型空心砌块的生产技术要素，指出利用工业废渣生产小型砌块符合国家的墙体改革和节能政策。